Respond in a positive way(positive comment),  to the post bellow, using one or more of the following approaches:Ask a probing question, substantiated with additional background information, and evidence.Share an insight from having read your colleagues’ postings, synthesizing the information to provide new perspectives.Offer and support an alternative perspective using readings from  the classroom or from your own review of the literature in the Walden  Library.Expand on your colleagues’ postings by providing additional insights or contrasting perspectives based on readings and evidence.                                                                                        Initial PostThe  research study’s focus was on the interventions to improve medication  adherence in people with multiple chronic conditions.  The population of  the study consisted of people over 70 years of age and having 3-4  chronic conditions.  A well-defined PICOT question helps to identify the  best available evidence to influence treatment (Echevarria, 2014).  The  PICOT question (P) The research study addressed medication adherence of  individual over the age of 70, (I) research involving eight studies  related to medication nonadherence, (C) Identified effective  interventions to improve medication adherence, and (O) evidence-based  treatment that assists in medication adherence would delay disease  progression.  Design             The design was a systematic review model by Cochrane Collaboration to  search, retrieve and appraise the quality and synthesis of the finding  of the RCT’s.  Out of the 248 abstracts only 97 were selected to be used  in full test and after an independent review by two separate reviewers,  only eight were chosen.  According to Polit, The Consort Checklist was  used to obtain the highest scores that could be used to generalize  results to similar groups.  “Consolidated Standards of Reporting Trials)  for reporting information for a randomized controlled trial, including a  checklist and flowchart for tracking participants through the trial,  from recruitment through data analysis.” (p. 723). The researchers used  the Intervention Group, Control Group, and Randomized Control Trials to  come up with the results.  Results             The researchers came to their conclusion after conducting a quality  assessment of the randomized, control trials examining medication  adherence using the CONSORT Group.  The research study did identify  weaknesses in the study. Several RTC’s had methodological problems, did  not identify all medical conditions, explanation of interventions used  (William, 2008).  Alternate Conclusion             There was a wealth of data in this research study that could be used to  explore several different issues related to medication adherence.   Researchers could have drawn a conclusion based on the data they  identified, what chronic conditions are individual most like or less  likely to be compliant with their medications.  They did find that  further research is needed on this subject.ReferencesEchevarria, I. &. (2014, February). To make your case, start with a PICOT question.  Retrieved from OVID:  https://ovidsp-tx-ovid-com.ezp.waldenulibrary.org/sp-3.33.0b/ovidweb.cgi?WebLinkFrameset=1&S=NAAIFPMHKIDDHDBONCDKIAJCHHLHAA00&returnUrl=ovidweb.cgi%3f%26Titles%3dS.sh.22%257c1%257c10%26FORMAT%3dtitle%26FIELDS%3dTITLES%26S%3dNAAIFPMHKIDDHDBONCDKIAJCHHLHAA0Polit, D. F. (2017). Nursing Research: Generating and Assessing Evidence for Nursing Practice. Philadelphia: Wolters Kluwer Health.William, A. M. (2008, July 4). Intervention to improve medication adherence in people with multiple chronic conditions: a systematic review.  Retrieved from Wiley Library Online: Retrieved From:  https://onlinelibrary-wiley-com.ezp.waldenulibrary.org/doi/full/10.1111/j.1365-2648.2008.04656.x